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Semax nasal spray, Diluent
Cognitive & Sleep

Buy Semax in the UK

Semax is a heptapeptide analogue of ACTH(4-10), registered for prescription in Russia, not authorised in the UK. 5mg vial or nasal spray. Research use only.

from £18.992 options

  • In UK stock Sent from Britain
  • Leaves the same day When ordered before 2pm
  • Tracked shipping No charge over £75
  • Certificate of analysis Available on request

Prices for Semax start at £18.99, and all of it is already in British stock at diluents.co.uk rather than sourced to order. It is offered as nasal spray and vial. Order on a weekday before 2pm and the parcel leaves that day, tracked, in a box that gives no clue to its contents.

Because the parcel never leaves the country, nothing has to clear customs, no import charge falls due and nothing is held at a border. Each batch tests at ≥99% by HPLC, and a certificate of analysis for the stock you receive is available on request.

Tracked delivery costs £4.95, or nothing above £75. The ordering steps, one by one.

Every Semax size and format

2 to choose from
Semax Nasal spray Semax Nasal spray
£18.99
Semax 5mg vial Semax 5mg Vial · £7.60/mg
£37.99

Elsewhere on the Cognitive & Sleep shelf

Whole shelf →
DSIP DSIP
5mg £19.99

What is Semax?

Semax is a seven-residue peptide, Met-Glu-His-Phe-Pro-Gly-Pro, developed at the Russian Academy of Sciences' Institute of Molecular Genetics. It is an ACTH(4-10) analogue lacking ACTH's hormonal activity. It is registered in the Russian Federation as a prescription pharmaceutical, but holds no UK marketing authorisation.

Specification

Residues7
SequenceMet-Glu-His-Phe-Pro-Gly-Pro
Analogue ofThe ACTH(4-10) fragment
Molecular formulaC37H51N9O10S
Molecular weight813.9
CAS80714-61-0
Purity≥99% by HPLC
FormatsVial (5mg) and nasal spray
Certificate of analysisAvailable on request

Which studies have looked at Semax?

For Semax, the published record runs to 1 human study, a claim few other compounds in this catalogue share. Grouped by study model, here is what each paper examined:

Studies in people

  • Semax in stroke rehabilitation (Gusev, Martynov et al.), Human, 110 patients, NON-randomised and not placebo-controlled

In-vitro and animal studies

  • Semax and BDNF expression in rat brain, Rat, brain tissue (PMID 14556513)
  • BDNF and NGF gene expression changes following Semax administration, Rat, regional brain gene expression (PMID 19662538)

Every entry names what a study examined. No entry reports an effect in a person, and nowhere does the site give instructions on how to use anything.

Buying Semax in the UK: where and how

How does ordering work?

Choose a strength, add it to the basket and go through checkout; no account is needed. An order confirmation comes through at once, and since the site never takes a card, the payment details arrive separately by email.

What difference does UK stock make?

Your Semax is sent from a warehouse in Britain, so it skips customs, attracts no import charge and loses no days travelling from overseas. A courier collects it the same afternoon if the order is in before 2pm on a working day; the parcel then travels tracked in a plain outer box.

What do you receive?

Purity≥99%, measured by HPLC
LabellingCompound name, strength, format, purity and a research-use statement
Certificate of analysisAvailable on request for the stock you receive
DeliveryUK addresses only, tracked. £4.95, or free over £75
ReturnsWithin 14 days for sealed, unopened items, see the terms

Semax reconstitution

What ships is a dry, freeze-dried cake, and bacteriostatic water is what turns it into a solution. The volume you choose sets how strong that solution ends up. Water only spreads the contents out; it never adds to or takes from the milligrams sealed in the vial.

2.50 mg/mlConcentration
0.100 mlHolds 0.25mg
10.0 unitsOn a U-100 syringe
25 mcgPer unit of that syringe

The figures above are volumes and concentrations of a solution; none of them is a dose, and no guidance on dosing, protocols or administration is given on this site.

The figures open on the 5mg vial with 2ml added, and they update as soon as either control changes. For the syringe-scale conversion, a comparison of the waters and the keeping time of a mixed vial, use the full reconstitution calculator.

mg/ml reached for each vial size and volume of water
Vial+ 1ml+ 2ml+ 3ml+ 5ml
5mg 5 mg/ml2.5 mg/ml1.67 mg/ml1 mg/ml

As a worked case, the 5mg vial with 2ml of bacteriostatic water comes to 2.5 mg/ml, which is simply the label milligrams divided by the millilitres added. Every number in the table is the concentration of a solution, never a dose. Dosage, protocol and administration guidance appear nowhere on this site.

Asked about mixing Semax

How to reconstitute Semax?

Once the vial is at room temperature and the stopper has been swabbed, the bacteriostatic water goes in along the glass wall, away from the powder. Keep rolling until the solution is clear, and do not shake. The volume chosen fixes the concentration; for the 5mg vial, 1ml gives 5 mg/ml, 2ml gives 2.5 mg/ml, 3ml gives 1.67 mg/ml, 5ml gives 1 mg/ml.

How to reconstitute Semax 10mg?

Spread through the four usual volumes, 10mg works out like this: 1ml gives 10 mg/ml, 2ml gives 5 mg/ml, 3ml gives 3.33 mg/ml, 5ml gives 2 mg/ml. Here, Semax is sold as 5mg; the arithmetic is the same for any vial, label milligrams divided by millilitres added.

What care does the vial need?

  • A chilled vial should warm to room temperature first.
  • Before every entry through the stopper, clean it with an alcohol swab.
  • Let the water run down the inside wall of the glass; never squirt it onto the cake.
  • Roll, never shake: foam means protein has been damaged, and rolling between the fingers avoids it.
  • Expect a few minutes before it dissolves fully; a correctly mixed vial ends up clear.

Semax storage

Vial, still sealedKeep it dark, dry and cool; the freezer suits long-term storage best.
After mixingRefrigerate it upright and shaded. A mixed solution should never be frozen.
Nasal spraySupplied as a solution; straight into the fridge on arrival.

What is its shelf life?

Typical keeping times for lyophilised peptides in general
ConditionTypical life
Unopened, in a −20 °C freezerYears. No other condition preserves a lyophilised peptide as well
Unopened, in a fridge at 2–8 °CMonths
Unopened, at room temperatureWeeks. It copes with the time in transit but should not be kept like this
Mixed, in the fridgeWeeks rather than months. With bacteriostatic water added, the usual working figure is four weeks, and making that possible is the job of its preservative
Mixed, then frozenNot recommended. Peptides are torn by ice crystals, and each freeze–thaw cycle compounds the damage

These are the standard figures for lyophilised peptides in general; no stability study on a single batch produced them. Time is gained by keeping it cold and dry, and lost to damp, warmth, light and rough handling. A certificate of analysis is available on request.

Here it is supplied strictly as an unlicensed compound for laboratory research use only. No UK marketing authorisation covers Semax and it is not a licensed medicine, nor is it intended for human or veterinary use, or for food.

Compounds of this kind are not controlled drugs, and they can lawfully be sold as laboratory material; it is selling or marketing them for use by people that the law does not allow. That boundary is why this site carries no dose, protocol, route, frequency or medical claim, and why an emailed request for one is declined as well.

Some molecules in this range are also present in a licensed medicine marketed under a brand name. Its authorisation covers only the finished product for which it was granted, not the molecule in any other setting. Read the full terms.

Research use only. Diluent is not a pharmacy, and none of its compounds is a licensed medicine: everything is sold for laboratory research, with no dosage, protocol or administration guidance given. Not intended for human or veterinary use, or for use in food.

Questions about Semax

Is Semax approved in any country?

The Russian Federation lists it as a registered prescription pharmaceutical; the UK and the EU do not approve it.

Which formats can I buy?

Either a ready-mixed nasal spray or a vial holding 5mg of freeze-dried powder.

How to buy Semax?

In the UK, diluents.co.uk supplies Semax in one 5mg size only, as a ready-mixed nasal spray and vials, priced from £18.99. With the stock already in Britain, there is no clearance to wait on, no import charge and no risk of a border stop. Per milligram, that works out at £7.60. Because it is supplied as freeze-dried powder, the concentration is whatever you choose when it is mixed. Orders placed before 2pm on a weekday go out the same day, tracked and in plain packaging. Each batch goes through third-party lab testing and returns an HPLC result of ≥99%; the certificate covering yours is available on request, and for the steps, see how to order.

What does Semax cost?

Prices begin at £18.99 with the nasal-spray. Each of the 2 options carries a separate price and a separate per-milligram rate. Delivery costs £4.95, and above £75 there is no charge at all.

Does Semax need to be refrigerated?

Unopened and dry, it lasts for years in a freezer at −20 °C, for months refrigerated at 2–8 °C and for weeks at room temperature; the colder and drier the conditions, the longer it keeps. Once mixed with bacteriostatic water it belongs upright in the fridge, where four weeks is the usual working figure. A mixed vial must never be frozen, because ice crystals rip peptides apart and every freeze–thaw cycle repeats the damage.

Is Semax legal in UK?

Our Semax is supplied strictly for laboratory research, as an unlicensed research compound and for no other purpose. No UK marketing authorisation covers the product we sell, so it is not a licensed medicine; it is also not for human or veterinary use. Nor are we a pharmacy.

Can I see a certificate for your Semax, and what purity is it?

Yes. HPLC puts it at ≥99%, and on request we send the certificate of analysis that matches the material in your order. To check where current stock stands before you place an order, just ask and we will tell you.

References

  1. Semax and BDNF expression in rat brain. PMID 14556513
  2. BDNF and NGF gene expression changes following Semax administration. PMID 19662538
  3. Semax in stroke rehabilitation (Gusev, Martynov et al.). Zhurnal Nevrologii i Psikhiatrii, 2018

Follow any link to read the original paper in full.